Executive Briefing

The next 40 million GLP-1 users

How they’re different and what it means for food businesses. Also: Why Grüns won.

Gruns
Grüns Day.

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Ozempic and other GLP-1 medications — highly effective, life-changing weight-loss drugs — are among the most important forces shaping consumption today and in the future. Now they’re about to go mass.

In a new research report published last week, Morgan Stanley projected that the number of Americans on GLP-1s will quadruple over the next decade. Specifically, it estimates that 55 million Americans — around 15% of the US population — will be on a GLP-1 medication by 2035, up from around 13 million at the end of 2025.

(One quick note: These numbers are actually much lower than other estimates I’ve seen. For instance, a KFF poll from last November found that 12% of US adults said they were currently taking a GLP-1 drug, implying around 30 million active users — roughly double Morgan Stanley’s estimate. Why the gap? One thought is that Morgan Stanley is undercounting the booming compounded market — people getting GLP-1s through Hims and less reputable online pharmacies. There’s also a lot of churn of people going on and off GLP-1s, and probably some noise in self-reported survey data. So it’s actually somewhat tricky to model an active-user count. And different models are based on different assumptions, making them tough to compare apples-to-apples. My guess is that the real number is somewhere in the middle.)

Either way, most of that growth is forecast to happen in the next few years, driven by lower prices, new pill-based options that are far less invasive than today’s injectables, and expanded Medicare coverage.

CHART OF THE DAY

The key question for The New Consumer has always been how GLP-1s — which cause users to consume fewer calories, and eat and drink differently — will affect consumption and spending. Especially once tens of millions of people are on them.

What’s happening now?

For a while, there were concerns that the food industry could get hit hard if people just stop buying certain products. So far, that hasn’t happened: Hershey’s is still growing, the J.M. Smucker Company is still growing, etc. Part of that is diversification, part is that the GLP-1 population is still relatively small, and part is that people tend to go back to some previous habits when they stop taking GLP-1s.

But people who are on GLP-1s do eat less — that’s the whole point. Around half of today’s users consume 20%+ fewer calories, according to Morgan Stanley’s research. And they eat differently, but not that differently: Today’s users tend to say they’re cutting back on the number of meals or snacks per day, or eating smaller portions, but generally not both.

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Dan Frommer

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